Computer-based technique for cell aggregation analysis and cell aggregation in in vitro chondrogenesis

Apparatus for measuring cell aggregation in vitro.

Small Molecule-BIO Accelerates and Enhances Marrow-Derived Mesenchymal Stem Cell in Vitro Chondrogenesis

Background: Hyaline cartilage defects exhibit a major challenge in the field of orthopedic surgery owing to its limited repair capacity. On the other hand, mesenchymal stem cells (MSCs) are regarded as potent cells with a property of cartilage regeneration. We aimed to optimize marrow-derived MSC chondrogenic culture using a small bioactive molecule referred to as BIO. Methods: MSCs from the ma...

Cell Aggregation

Platelets will normally adhere to ‘damaged’ vessel walls and to other ‘activated’ platelets in flowing blood (1); platelets adhere from flowing whole blood onto vessel segments (2) and onto solid surfaces in flow chambers coated with extracellular matrix or purified adhesive proteins ( 3-5). Neutrophils can adhere to each other and to platelets in flowing suspension (6) or adhere to platelets i...

A mathematical model of liver cell aggregation in vitro.

The behavior of mammalian cells within three-dimensional structures is an area of intense biological research and underpins the efforts of tissue engineers to regenerate human tissues for clinical applications. In the particular case of hepatocytes (liver cells), the formation of spheroidal multicellular aggregates has been shown to improve cell viability and functionality compared to tradition...

Antioxidant activity of polyphenolic myricetin in vitro cell-free and cell-based systems

Myricetin (Myc) is one of the most important flavonoids in diet due to its abundance in foods with the highest antioxidant activity. The antioxidant activity of Myc was studied in cell-free and cell-based systems to evaluate the ROS protection efficiency of Myc. The studies were based on the assessment of reducing power of Myc according to ferric ion reduction and intracellular ROS level measur...